Business Performance Director (Chief of Staff)

Company: Amgen
Location: Cambridge
Posted on: February 7, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Business Performance Director (Chief of Staff) What you will do Lets do this. Lets change the world! In this vital role you will provide leadership across a broad portfolio of complex, high-visibility initiatives and act as an enterprise connector across Amgens site network and global functions. The Business Performance Director is a senior site leadership role responsible for advancing the strategic, operational, and cultural performance of the Amgen Massachusetts (AMA) site. Reporting to the AMA Site Head, this leader serves as a trusted advisor to the Site Leadership Team (SLT), owning site-wide strategy execution, business performance management, and enterprise-level initiatives that enhance resilience, productivity, and engagement. This role operates with significant autonomy and influence, integrating strategy, operations, governance, and external engagement across the AMA site. Specific responsibilities include, but are not limited to: Site Strategy & Business Performance Leadership Lead AMA site strategic planning, including development, execution, tracking, and refinement of 1-year, 3-year, and long-range site strategies aligned to Amgens LRP. Translate site strategy into an integrated portfolio of prioritized initiatives with clear performance metrics, milestones, and accountability. Own site-wide performance management, including dashboards, quarterly business reviews, productivity portfolios, and transformation initiatives. Serve as a strategic thought partner to the Site Head and AMA SLT, guiding decision-making on priorities, trade-offs, and risk. Executive Leadership & Governance Act as a senior member of the AMA Site Leadership Team, shaping agendas, facilitating strategic discussions, and independently driving follow-through on leadership decisions. Lead high-visibility, cross-site and cross-functional initiatives requiring coordination across PD, Operations, Corporate Affairs, Facilities, HR, Finance, Technology, and EHS. Perform Chief-of-Stafflike responsibilities for the Site Head, including preparation of executive-level materials, leadership visits, and enterprise presentations. Represent AMA in executive forums, site network discussions, and external engagements as delegated by the Site Head. Operational Excellence, Risk & Resilience Oversee critical site-wide programs including operational excellence, digital transformation, business continuity, risk management, and continuous improvement. Develop and maintain the site risk profile, mitigation strategies, and escalation pathways in partnership with the AMA SLT. Ensure operational rigor and resilience across the AMA site, proactively identifying risks and driving mitigation strategies. Facilities, Site Services & Utilization Partner with Facilities, Operations, and EHS leaders to ensure AMA maintains high standards for safety, functionality, and employee experience. Own site utilization strategy, space planning, and site calendar governance to optimize campus use and support evolving ways of working. Collaborate on the deployment and optimization of Amgens hybrid work and FlexSpace models at AMA. Engagement, Culture & External Partnerships Partner with Corporate Affairs and site communications to shape consistent, high-impact internal messaging and site engagement strategies. Foster strong engagement across Employee Resource Groups (ERGs), site councils, and cross-functional communities. Scientific and Business acumen to strengthen Amgens presence within the Boston/Cambridge ecosystem by developing strategic external partnerships with academic, industry, government, and community organizations. Act as an ambassador for AMA, reinforcing Amgens culture, values, and patient-focused mission. Leadership & Talent Development Build strong, trust-based relationships across functions, levels, and geographies. Model inclusive leadership behaviors and drive a culture of accountability, collaboration, and continuous improvement. What we expect of you We are all different, yet we all use our unique contributions to serve patients! The Business Performance Director we seek is a collaborative, forward-looking leader with these qualifications. Basic Qualifications: Doctorate degree and 4 years of strategic operations, or business performance/chief of staff experience OR Masters degree and 7 years of strategic operations, or business performance/chief of staff experience OR Bachelors degree and 9 years of strategic operations, or business performance/chief of staff experience Preferred qualifications: Progressive leadership experience in site operations, strategy, or enterprise business performance within a pharmaceutical, biotechnology, or healthcare organization. Demonstrated ability to operate at the executive level, influencing senior leaders and synthesizing complex information into clear recommendations. Experience leading site-wide or enterprise-wide transformation initiatives. Strong executive presence with exceptional written, verbal, and presentation skills. Proven ability to lead in matrixed, highly complex environments. Experience managing risk, resilience, and business continuity programs. Track record of delivering results through a collaborative, inclusive, and professional leadership style. Experience working across global or multi-site organizations. What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, New Bedford , Business Performance Director (Chief of Staff), Human Resources , Cambridge, Massachusetts